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. 2024 Mar 6;42(2):229–239. doi: 10.1007/s10637-024-01418-2

Fig. 3.

Fig. 3

A Results are an average of 4 separate experiments. After 6 h of treatment, SMARCA4 mRNA levels increased significantly in KRAS-wt cells treated with CBZ (p < 0.01). These levels are significantly higher than in KRAS-mut cells treated with CBZ (p < 0.01). B Results are an average of 5 separate experiments. After 24 h of treatment, SMARCA4 mRNA levels increased significantly in KRAS-wt cells treated with CBZ (p < 0.01) and decreased significantly in KRAS-mut cells treated with CBZ (p < 0.01). The difference between KRAS-mut cells and KRAS-wt cells treated with CBZ was also significant (p < 0.001)