Fig. 5.

A WT-KRAS docked with CBZ forms shows the similar binding conformations of CBZ and t-CBZ, while CBZ-q binds in a different orientation. B G13D docked with CBZ forms shows similar binding conformations of CBZ and t-CBZ, while CBZ-q binds in a different orientation. The orientations of each CBZ form have visual differences than when bound to WE-KRAS. C SMARCA4 docked with CBZ forms shows similar docking sites for CBZ and t-CBZ in different orientations, while CBZ-q most favorably binds elsewhere