Fig. 4.

Inhibition of SOD and CAT by high Cd²⁺ contributes to H₂O₂ dominance. Time course of SOD (A) (n = 5–11) and CAT (B) (n = 18–19) activities after Cd²⁺ exposure. C Transient transfection of empty vector (EV), human SOD1 or CAT plasmids for 24 h followed by 6 h Cd²⁺ exposure. Toxicity was determined by MTT assay (n = 4–5). Comparisons between Cd²⁺ treated and control samples were performed using one-way ANOVA and Holm–Sidak post hoc test at each timepoint