Detection of HTLV-2 proviral integration sites in transformed populations of T lymphocytes. Southern blot analyses of DNA from HTLV-2 transformants determined to be clonal by TCRβ rearrangement analysis were digested with HindIII and hybridized with HTLV-2 probe pMO-4, which consisted of inserts of the entire HTLV-2 genome (57) (kindly provided by George Shaw, University of Alabama, Birmingham, Ala.). Lane MO, LAMP/MO; lanes 1 to 9, HTLV-2 transformants; lane 10, negative control (PBLs from HTLV-negative donor).