Table 6.
Effects of nickel and benzo [a] anthracene on the level of protein, protein thiol, and carbonyl in the kidney of rats after 12 and 24 weeks of exposure
| Parameters | Duration (Weeks) | Group | ||
|---|---|---|---|---|
|
|
|
|||
| Kidney | Control | Nickel | Benzo (a) anthracene | |
| Protein Carbonyl (×10-5 nmol/mgprot) | 12 | 0.22±0.05 | 0.33±0.04# | 0.72±0.01* |
| 24 | 4.63±0.46 | 4.45±0.16# | 3.33±0.54# | |
| Protein thiol (mM) | 12 | 1.13±0.16 | 0.88±0.24# | 1.16±0.21# |
| 24 | 2.65±0.13 | 2.18±0.04* | 2.06±0.13* | |
| Total Protein (g/dl) | 12 | 3.61±1.01 | 3.25±0.30# | 3.77±0.22# |
| 24 | 2.58±0.10 | 2.48±0.03# | 8.90±1.48* | |
Values were expressed as mean ± SEM.
*
represent significant different with control.
#
represent insignificant different with control.
Keys: Control: rats group fed with normal rats feed without any contamination. Nickel: rats group fed with nickel contaminated feed. Benzo (a) anthracene: rats group fed with benzo (a) anthracene contaminated feed.