Table 3. Comparison of clinical outcomes, treatment characteristics, and inflammatory biomarkers between patients with and without sepsis.
| Variable | Sepsis (n=147) | Non-sepsis (n=152) | P value |
|---|---|---|---|
| Transferred to ICU† | 34 (28.8) | 0 (0) | <0.001 |
| LOS in hospital, d | 7.87±3.90 | 6.632±2.97 | 0.120 |
| Mortality | 29 (19.73) | 1 (0.66) | <0.001 |
| White blood cell count (×109/L) | 10.11±5.7 | 7.66±3.39 | <0.001 |
| Lymphocyte count (×109/L) | 2.56±9.88 | 3.311±9.20 | 0.512 |
| Platelet count (×109/L) | 194.62±101.96 | 296.11±97.56 | <0.001 |
| Lactate (mmol/L) | 1.61±1.52 | 1.32±0.69 | 0.336 |
| IL-6‡ (U/mL) | 0.000 | ||
| <7 | 9 (10.11) | 37 (36.63) | |
| 7–149.9 | 63 (70.77) | 61 (60.40) | |
| 150–250 | 3 (3.37) | 3 (2.97) | |
| >250 | 14 (15.73) | 0 (0) | |
| CRP§ (mg/L) | <0.001 | ||
| <10 | 29 (30.85) | 43 (46.74) | |
| 10–24.9 | 9 (9.57) | 20 (21.74) | |
| 25–49.9 | 17 (18.09) | 12 (13.04) | |
| 50–99.9 | 15 (15.96) | 13 (14.13) | |
| ≥100 | 24 (25.53) | 4 (4.35) | |
| PCT¶ (ng/mL) | <0.001 | ||
| <0.05 | 14 (9.93) | 70 (48.61) | |
| 0.05–1.99 | 92 (65.25) | 69 (47.92) | |
| ≥2 | 35 (24.82) | 5 (3.47) | |
| Glucocorticoid therapyǁ | 84 (72.41) | 72 (47.37) | <0.001 |
| Paxlovid therapy# | 26 (26.26) | 38 (25.00) | 0.823 |
| Azvudine therapy# | 4 (0.40) | 5 (3.29) | 0.754 |
Data are presented as number (percentage) or mean standard deviation. †, 269 patients who were initially admitted to the general ward were analyzed; ‡, the data of 190 patients were analyzed because of missing data; §, the data of 186 patients were analyzed because of missing data; ¶, the data of 285 patients were analyzed because of missing data; ǁ, the data of 268 patients were analyzed because of missing data; #, the data of 251 patients were analyzed because of missing data. CRP, C-reactive protein; ICU, intensive care unit; IL-6, interleukin-6; LOS, length of stay; PCT, procalcitonin; SD, standard error.