Table 2.
The aPL and other laboratory profiles of the patients
| Low titers (n = 92) | Medium–high titers (n = 32) | P | |
|---|---|---|---|
| aβ2GP1-IgG positive | 3 (3.3%) | 13 (40.6%) | < 0.001 |
| aβ2GP1-IgM positive | 13 (14.1%) | 10 (31.3%) | 0.032 |
| ACL-IgG positive | 9 (9.8%) | 7 (21.9%) | 0.147 |
| ACL-IgM positive | 75 (81.5%) | 12 (37.5%) | < 0.001 |
| LA positive | 3 (3.8%) | 2 (7.4%) | 0.812 |
| Single positive | 83 (90.2%) | 26 (81.3%) | 0.305 |
| Double positive | 9 (9.8%) | 4 (12.5%) | 0.923 |
| Triple positive | 0 (0%) | 2 (6.3%) | 0.109 |
| ANA positive | 12/76 (15.8%) | 7/28 (25%) | 0.281 |
| Anti-SSA antibody positive | 7/72 (9.7%) | 3/27 (11.1%) | 1.000 |
| Anti-SSB antibody positive | 0 (0%) | 1/27 (3.7%) | 0.614 |
| TGAb positive | 5/75 (6.7) | 1/27 (3.7%) | 0.933 |
| TPOAb positive | 9/75 (12) | 3/27 (11.1%) | 1.000 |
| IgG (g/L) | 12.28 ± 2.14 | 13.24 ± 2.40 | 0.707 |
| IgA (g/L) | 2.28 (1.91, 2.75) | 2.90 (1.87, 3.31) | 0.445 |
| IgM (g/L) | 2.06 ± 0.86 | 1.93 ± 0.79 | 0.072 |
| C3 (g/L) | 1.17 (1.10, 1.31) | 1.33 (1.18, 1.50) | 0.124 |
| C4 (g/L) | 0.22 (0.18, 0.29) | 0.26 (0.15, 0.31) | 0.566 |
| CRP (mg/L) | 0.75 (0.33, 2.45) | 3.26 (2.47, 5.11) | 0.144 |
| ESR (mm/h) | 11 (5, 16) | 19.5 (11.77, 25) | 0.006 |
aβ2GP1 anti-β2-glycoprotein 1 antibodies, aCL anticardiolipin antibodies, LA lupus anticoagulants, ANA antinuclear antibody, TGAb thyroglobulin autoantibodies, TPOAb anti-thyroperoxidase antibodies, ESR erythrocyte sedimentation rate, CRP C-reactive protein