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. 2024 Feb 6;15(1):1–9. doi: 10.5365/wpsar.2024.15.1.1051

Table 2. Change in cycle threshold values from baseline to day 3 and association of the change with vaccination status for health-care workers with COVID-19, Brunei Darussalam, 15 February to 15 March 2022.

Change in Ct values No. of HCWs Ct value at day 3a
10–20 21–30 > 30 Negative
Ct value at day 0
   10–20 447 154 (34.5) 279 (62.4) 9 (2.0) 5 (1.1)
   21–30 273 132 (48.4) 109 (39.9) 19 (7.0) 13 (4.8)
   ≥ 30 251 87 (34.7) 41 (16.3) 7 (2.8) 116 (46.2)
   Rapid antigen test positive 150 71 (47.3) 73 (48.6) 1 (0.7) 5 (3.3)
   Total 1121 444 502 36 139
Change in Ct values and
association with vaccination
No. of HCWs Ct valueb P c
Day 0 Day 3
Total 975 20.9 (12.9) 21.5 (7.3) 0.74
Vaccination status
   2 doses 54 22.1 (11.3) 22.35 (8.3) 0.48
   3 doses 921 20.9 (12.9) 21.5 (7.1) 0.56
Booster period
   Within < 1 month 36 22.5 (15.9) 24.7 (11.8) 0.74
   Within 1–3 months 393 21.3 (14.4) 21.9 (7.5) 0.85
   Within > 3 months 546 20.7 (11.9)
20.9 (6.9) 0.41

Ct: cycle threshold; HCW: health-care worker.

a Values are number (%).

b Values are median (interquartile range).

c P-values were calculated using the paired t-test.