Table 1.
Demographic and clinical characteristics of children with persistent diarrhea before, during, and after treatment.
| Characteristic | Control group (N = 41) | Clausy group (N = 40) | p value | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Before treatment | During and after treatment | Before treatment | During and after treatment | Before treatment | During and after treatment | ||||
| Day 0 | Day 3 | Day 5 | Day 0 | Day 3 | Day 5 | Day 0 | Day 3 | Day 5 | |
| Age (months) | |||||||||
| 3 ≤ x ≤ 12, n (%) | 40 (97.56) | 38 (95.00) | 0.62a | ||||||
| 12 < x ≤ 24, n (%) | 1 (2.44) | 2 (5.00) | |||||||
| Gender | |||||||||
| Male, n (%) | 24 (58.54) | 22 (55.00) | 0.75b | ||||||
| Female, n (%) | 17 (41.46) | 18 (45.00) | |||||||
| Covid-19 infection | |||||||||
| Mother, n (%) | 22 (53.66) | 24 (60.00) | 0.56b | ||||||
| Children, n (%) | 4 (9.76) | 3 (7.50) | > 0.9999a | ||||||
| Weight | |||||||||
| Average ± SD | 7.24 ± 1.34 | 7.26 ± 1.34 | 7.3 ± 1.32 | 7.03 ± 1.22 | 7.06 ± 1.21 | 7.08 ± 1.21 | 0.44c | 0.46c | 0.42c |
| Weight for age Z-score | |||||||||
| < −2SD, n (%) | 1 (2.44) | 0 (0.00) | > 0.9999a | ||||||
| ≥ −2SD and ≤ 2SD, n (%) | 40 (97.56) | 40 (100) | > 0.9999a | ||||||
| > 2SD, n (%) | 0 (0.00) | 0 (0.00) | |||||||
| Height | |||||||||
| Average ± SD | 64.63 ± 4.82 | 64.83 ± 4.09 | 0.85d | ||||||
| Height for age Z-score | |||||||||
| < −2SD, n (%) | 1 (2.44) | 0 (000) | > 0.9999a | ||||||
| ≥ −2SD and ≤ 2SD, n (%) | 39 (95.12) | 40 (100) | 0.49a | ||||||
| > 2SD, n (%) | 1 (2.44) | 0 (0.00) | > 0.9999a | ||||||
| Typical symptoms | |||||||||
| Median days of persistent diarrhea before treatment | 17 | 16 | 0.63c | ||||||
| Median stools a day | 6 | 4 | 3 | 6 | 4 | 2 | 0.43c | 0.06c | < 0.0001c |
| Stools a day of ≥ 3, n (%) | 41 (100) | 36 (87.8) | 34 (82.93) | 40 (100) | 32 (80.0) | 15 (37.5) | > 0.9999a | 0.34b | 0.0001b |
| 3–5 stools a day | 18 (43.90) | 25 (60.98) | 30 (73.17) | 18 (45) | 27 (67.5) | 15 (37.5) | 0.92b | 0.54b | 0.0016b |
| 6–7 stools a day | 16 (39.02) | 10 (24.39) | 4 (9.76) | 15 (37.5) | 5 (12.5) | 0 (0.00) | 0.89b | 0.18b | 0.12a |
| ≥ 8 stools a day | 7 (17.07) | 1 (2.44) | 0 (0.00) | 7 (17.5) | 0 (0.00) | 0 (0.00) | 0.96b | > 0.9999a | |
|
Presence of fecal mucus, n (%) |
39 (95.12) | 37 (90.24) | 30 (73.17) | 39 (97.50) | 26 (65.0) | 18 (45.0) | > 0.9999a | 0.008a | 0.01b |
|
Diaper stool types 4-5B, n (%) |
38 (92.68) | 33 (80.49) | 21 (51.22) | 32 (80.0) | 20 (50.0) | 10 (25.0) | 0.12a | 0.19b | 0.02b |
aFisher’s Exact test; bChi-Square test; c Mann–Whitney test; d t-test.
Significant values are in bold.