Table 2.
Endocrinology findings pre-surgery and on follow-up.
| Patients number | Pre OP GH (ng/ml) | Pre OP IGF (ng/ml) | Post OP GH (ng/ml) | Post OP IGF (ng/ml) | Other hormonal abnormality | Medication | Signs and symptoms before surgery |
|---|---|---|---|---|---|---|---|
| #1 | 3.6 (0.03–2.4) | 602 (72–421) | 0.45 (0–3) | 227 (63–323) | High prolactin: reversed | Cabergoline levothyroxine | Increased size lumbosacral pain |
| #2 | 20.9 | 925 (204) | 2.04 (0.07–8.3) | 241 (54–240) | High TSH: reversed | – | Increased size |
| #3 | 33.13 (up to 12.4) | 482 (60–271) | 1.8 (0.32–5.06) | 243 (35–245) | – | – | Increased size |
| #4 | 2.25 (0.1–10) | 460 (69–200) | 0.51 (0.06–6.88) | 231.8 (54–204) | – | Levothyroxine | Increased size headache vision loss |
| #5 | 9.81 (0–4) | 797 (95–165) | NL | NL | – | Levothyroxine | Increased size right hemiparesis |
| #6 | 8 (0–4) | 483 (271–550) | NL | 173 (86–196) | – | – | Increased size headache |
| #7 | 9 (0–18) | 746 (0–160) | 0.52 (0–18) | 181.6 (54–204) | – | – | Increased size headache sweating hyperglycemia increased weight |
| #8 | 1.2 (0–8) | 323 (43–241) | NL | NL | Transient diabetes insipidus | Cabergoline | Increased weight blurry vision |
| #9 | 11 (0.12–10) | 425.5 (29–204) | 4.3 (0–1.23) | 120 (0–244) | High Prolactin: Reversed High FSH: Reversed low TSH after surgery | Sandostatin LAR levothyroxine | Increased size |
| #10 | 3.1 (0.02–1.23) | 1,032 (82–242) | 0.31 (0–2.47) | 230 (83–232) | – | Cabergoline | Increased weight increased size |
| #11 | 21 (0.2–4.7) | 1,321 (115–370) | 0.51 (0.02–4.77) | 642 (96–227) | High Prolactin: Reversed | Sandostatin LAR cabergoline DDAVP nasal spray | Headache increased weight increased size blurry vision |
| #12 | High | 569 (106–546) | 0.88 (<9) | 128 (<216) | Low TSH before and after Surgery | Levothyroxine | Increased size increased weight blurry vision |
| #13 | 7.7 (0–2.5) | 398 (69–343) | 0.1 (0–2.5) | 185 (97–292) | – | – | Increased size |
| #14 | 8.92 (0–2) | 501.6 (87–415) | 0.31 (0–66) | 280.9 (115–230) | – | – | Headache increased weight increased Size |
| #15 | 10.73 | 299 | 0.48 (0.1–10) | 195 (73–243) | High prolactin: reversed | – | Increased size reduced hearing blurry vision |
| #16 | 6.9 (0.06–6.8) | 370 (67–230) | 1.46 (0.1–10) | 222.9 (69–227) | – | Sandostatin LAR | Paresthesia Increased size |
| #17 | 1.95 (0–5) | 168 (97–292) | 0.03 (0–66) | 177 (97–292) | – | – | Headache increased weight increased size |
NL, normal.