TABLE 2.

ADME properties of tested compounds.

Entry	Compound	LogP	Mol. Wt	H-donor	H-acceptor	TPSA	Lipinski #violations
1	COL
2	1	2.00	169.18	0	4	59.32	0
3	2	3.06	225.28	0	4	59.32	0
4	3	2.81	245.27	0	4	59.32	0
5	4	2.50	245.27	0	4	59.32	0
6	5	2.39	217.22	0	4	59.32	0
7	6	2.57	247.25	0	5	68.55	0
8	7	2.55	285.22	0	7	59.32	0
9	8	2.30	235.21	0	5	59.32	0
10	9	2.52	231.25	0	4	59.32	0
11	10	2.29	223.25	0	4	87.56	0
12	11	2.98	305.33	0	4	59.32	0
13	12	3.18	307.34	0	4	59.32	0

COL, colchicine. Bold values are numbers of synthesized compounds.