Table 1.
Main evidence on MetS in PSD.
| Disorder | MetS prevalence | Main putative risk factors for MetS |
Factors associated with MetS |
|---|---|---|---|
| PSD | ∼30% | Sedentary lifestyle Antipsychotic medications Genetic predisposition Substance abuse and addiction (e.g. smoking) Diet Pro-inflammatory state Stress Insufficient somatic care |
↑morbidity ↑ mortality ↑cardiovascular risk |
| SCZ | ∼50% |
↑ cognitive impairment ↑ positive symptoms |
|
| SCZaff | ∼70% | ||
| BD | ∼60% |
↑ rapid cycling ↑ suicide risk ↓executive function |
Prevalence, risk factors, and implications of MetS in PSD. BD, Bipolar Disorder; MetS, Metabolic Syndrome; PSD, Psychotic Spectrum Disorder; SCZ, Schizophrenia; SCZaff, Schizoaffective disorder. References are provided in the text.
Upward arrows indicate an increase, downward arrows a decrease.