Table 2.
MR analysis of food intakes on cholelithiasis in complementary methods.
| Exposure | NSNP | MR_methodology | OR | LCI95 | UCI95 | P-value | Q-value | Pheterogeneity | MR_Egger_intercept | Ppeleiotropy | Rsquare | Fstat |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Alcohol | 33 | IVW_fe | 1.000 | 0.998 | 1.002 | 0.665 | 45.182 | 0.061 | 0.103 | 59.419 | ||
| MR_Egger | 0.989 | 0.980 | 0.998 | 0.027 | 38.613 | 0.163 | 0.000 | 0.029 | ||||
| Weighted_median | 0.999 | 0.996 | 1.003 | 0.731 | ||||||||
| IVW_mre | 1.000 | 0.997 | 1.002 | 0.716 | 45.182 | 0.061 | ||||||
| Beef | 9 | IVW_fe | 1.001 | 0.993 | 1.010 | 0.719 | 4.707 | 0.788 | 0.027 | 41.473 | ||
| MR_Egger | 0.978 | 0.921 | 1.037 | 0.478 | 4.055 | 0.773 | 0.000 | 0.446 | ||||
| Weighted_median | 1.002 | 0.992 | 1.012 | 0.704 | ||||||||
| IVW_mre | 1.001 | 0.995 | 1.008 | 0.639 | 4.707 | 0.788 | ||||||
| Bread | 23 | IVW_fe | 0.998 | 0.993 | 1.002 | 0.261 | 26.080 | 0.248 | 0.091 | 41.814 | ||
| MR_Egger | 1.011 | 0.987 | 1.036 | 0.365 | 24.529 | 0.268 | 0.000 | 0.262 | ||||
| Weighted_median | 1.000 | 0.994 | 1.007 | 0.929 | ||||||||
| IVW_mre | 0.998 | 0.993 | 1.002 | 0.302 | 26.080 | 0.248 | ||||||
| Cereal | 26 | IVW_fe | 1.001 | 0.996 | 1.005 | 0.695 | 30.270 | 0.214 | 0.002 | 45.030 | ||
| MR_Egger | 1.012 | 0.988 | 1.036 | 0.340 | 29.238 | 0.211 | 0.000 | 0.366 | ||||
| Weighted_median | 1.005 | 0.999 | 1.012 | 0.129 | ||||||||
| IVW_mre | 1.001 | 0.996 | 1.006 | 0.722 | 30.270 | 0.214 | ||||||
| Cheese | 40 | IVW_fe | 0.998 | 0.995 | 1.001 | 0.127 | 47.522 | 0.164 | 0.099 | 39.017 | ||
| MR_Egger | 1.001 | 0.983 | 1.019 | 0.952 | 47.388 | 0.141 | 0.000 | 0.746 | ||||
| Weighted_median | 0.998 | 0.993 | 1.002 | 0.352 | ||||||||
| IVW_mre | 0.998 | 0.994 | 1.001 | 0.166 | 47.522 | 0.164 | ||||||
| Coffee | 27 | IVW_fe | 1.001 | 0.998 | 1.005 | 0.561 | 23.107 | 0.627 | 0.185 | 72.712 | ||
| MR_Egger | 0.999 | 0.992 | 1.006 | 0.785 | 22.646 | 0.598 | 0.000 | 0.503 | ||||
| Weighted_median | 1.000 | 0.995 | 1.005 | 0.999 | ||||||||
| IVW_mre | 1.001 | 0.998 | 1.004 | 0.538 | 23.107 | 0.627 | ||||||
| CookedVegetable | 15 | IVW_fe | 0.990 | 0.983 | 0.997 | 0.006 | 10.212 | 0.747 | 0.032 | 37.584 | ||
| MR_Egger | 0.985 | 0.908 | 1.069 | 0.728 | 10.199 | 0.678 | 0.000 | 0.911 | ||||
| Weighted_median | 0.987 | 0.977 | 0.998 | 0.015 | ||||||||
| IVW_mre | 0.990 | 0.984 | 0.996 | 0.001 | 10.212 | 0.747 | ||||||
| DriedFruit | 28 | IVW_fe | 0.992 | 0.987 | 0.997 | 0.001 | 17.286 | 0.924 | 0.075 | 41.899 | ||
| MR_Egger | 1.000 | 0.966 | 1.035 | 0.999 | 17.066 | 0.907 | 0.000 | 0.643 | ||||
| Weighted_median | 0.992 | 0.985 | 0.998 | 0.016 | ||||||||
| IVW_mre | 0.992 | 0.988 | 0.996 | 0.000 | 17.286 | 0.924 | ||||||
| FreshFruit | 43 | IVW_fe | 0.998 | 0.993 | 1.003 | 0.420 | 43.998 | 0.387 | 0.040 | 45.950 | ||
| MR_Egger | 0.996 | 0.977 | 1.016 | 0.709 | 43.963 | 0.347 | 0.000 | 0.858 | ||||
| Weighted_median | 0.999 | 0.991 | 1.007 | 0.767 | ||||||||
| IVW_mre | 0.998 | 0.993 | 1.003 | 0.431 | 43.998 | 0.387 | ||||||
| Lamb | 18 | IVW_fe | 1.009 | 1.002 | 1.016 | 0.012 | 19.172 | 0.319 | 0.077 | 39.595 | ||
| MR_Egger | 0.998 | 0.950 | 1.049 | 0.941 | 18.953 | 0.271 | 0.000 | 0.673 | ||||
| Weighted_median | 1.013 | 1.002 | 1.023 | 0.015 | ||||||||
| IVW_mre | 1.009 | 1.002 | 1.016 | 0.018 | 19.172 | 0.319 | ||||||
| NonOilyFish | 10 | IVW_fe | 0.991 | 0.983 | 0.999 | 0.026 | 15.761 | 0.072 | 0.006 | 44.802 | ||
| MR_Egger | 0.987 | 0.932 | 1.046 | 0.672 | 15.726 | 0.046 | 0.000 | 0.897 | ||||
| Weighted_median | 0.988 | 0.976 | 0.999 | 0.039 | ||||||||
| IVW_mre | 0.991 | 0.981 | 1.001 | 0.092 | 15.761 | 0.072 | ||||||
| OilyFish | 40 | IVW_fe | 0.996 | 0.993 | 1.000 | 0.026 | 45.442 | 0.221 | 0.029 | 44.918 | ||
| MR_Egger | 0.995 | 0.977 | 1.012 | 0.545 | 45.398 | 0.191 | 0.000 | 0.850 | ||||
| Weighted_median | 0.999 | 0.994 | 1.004 | 0.792 | ||||||||
| IVW_mre | 0.996 | 0.993 | 1.000 | 0.040 | 45.442 | 0.221 | ||||||
| Pork | 10 | IVW_fe | 1.007 | 0.997 | 1.016 | 0.162 | 11.700 | 0.231 | 0.015 | 37.686 | ||
| MR_Egger | 0.991 | 0.899 | 1.092 | 0.854 | 11.546 | 0.173 | 0.000 | 0.752 | ||||
| Weighted_median | 1.009 | 0.996 | 1.022 | 0.162 | ||||||||
| IVW_mre | 1.007 | 0.996 | 1.018 | 0.220 | 11.700 | 0.231 | ||||||
| Poultry | 7 | IVW_fe | 1.010 | 1.000 | 1.021 | 0.046 | 5.239 | 0.514 | 0.009 | 32.539 | ||
| MR_Egger | 0.959 | 0.711 | 1.294 | 0.797 | 5.121 | 0.401 | 0.001 | 0.749 | ||||
| Weighted_median | 1.008 | 0.994 | 1.022 | 0.283 | ||||||||
| IVW_mre | 1.010 | 1.001 | 1.020 | 0.032 | 5.239 | 0.514 | ||||||
| ProcessedMeat | 17 | IVW_fe | 1.002 | 0.997 | 1.007 | 0.524 | 21.408 | 0.163 | 0.036 | 38.536 | ||
| MR_Egger | 0.957 | 0.923 | 0.993 | 0.035 | 15.351 | 0.426 | 0.001 | 0.028 | ||||
| Weighted_median | 1.004 | 0.996 | 1.011 | 0.327 | ||||||||
| IVW_mre | 1.002 | 0.996 | 1.007 | 0.582 | 21.408 | 0.163 | ||||||
| RawVegetable | 11 | IVW_fe | 0.997 | 0.987 | 1.007 | 0.537 | 12.480 | 0.188 | 0.023 | 38.333 | ||
| MR_Egger | 1.022 | 0.939 | 1.113 | 0.623 | 11.963 | 0.153 | 0.000 | 0.573 | ||||
| Weighted_median | 0.995 | 0.982 | 1.008 | 0.462 | ||||||||
| IVW_mre | 0.997 | 0.986 | 1.008 | 0.600 | 12.480 | 0.188 | ||||||
| Tea | 28 | IVW_fe | 1.000 | 0.997 | 1.003 | 0.862 | 16.259 | 0.948 | 0.067 | 60.812 | ||
| MR_Egger | 0.999 | 0.993 | 1.006 | 0.871 | 16.183 | 0.932 | 0.000 | 0.785 | ||||
| Weighted_median | 1.000 | 0.996 | 1.004 | 0.976 | ||||||||
| IVW_mre | 1.000 | 0.998 | 1.002 | 0.823 | 16.259 | 0.948 |