Table 2.
Demographic, history, clinical and biochemical characteristics of patients by recurrence of febrile seizures within the first 24 h from the first event.
| Patients with RFS (n = 52) |
Patients without RFS (n = 641) |
||||
|---|---|---|---|---|---|
| NoM | N (%) or median (IQR) | NoM | N (%) or median (IQR) | p-value | |
| Demographics | |||||
| Male | 52 | 32 (62) | 641 | 377 (59) | 0.7 |
| Female | 52 | 20 (38) | 641 | 264 (41) | |
| Age (months) | 52 | 17.5 (14–27) | 641 | 20 (15–27) | 0.2 |
| History and clinical characteristics | |||||
| Positive family history of febrile seizures | 52 | 12 (41) | 641 | 103 (32) | 0.3 |
| Respiratory tract infection | 52 | 28 (54) | 641 | 446 (70) | 0.02 |
| Acute otitis media | 52 | 1 (2) | 641 | 13 (2) | 1 |
| Gastroenteritis | 52 | 3 (6) | 641 | 14 (2) | 0.1 |
| Post-vaccination fever | 52 | 1 (2) | 641 | 12 (2) | 1 |
| Urinary tract infection | 52 | 0 | 641 | 1 (0.5) | 1 |
| Other diagnoses | 52 | 19 (37) | 641 | 153 (24) | 0.046 |
| Antipyretic use | 52 | 46 (88) | 641 | 477 (74) | 0.03 |
| Febrile seizures duration in minutes | 52 | 2 (1–3) | 641 | 2 (1–4) | 0.3 |
| Maximum fever temperature, °C | 52 | 39.3 (38.9–39.9) | 641 | 38.9 (38.4–39.3) | <0.001 |
| Blood tests | |||||
| White blood cell count, mm3 | 52 | 11,325 (9,092–15,260) | 640 | 13,165 (9,347–17,542) | 0.2 |
| C reactive protein, mg/dl | 52 | 1.2 (0.3–1.8) | 641 | 1.4 (0.3–1.7) | 1 |
| Sodium (direct potentiometry), mEq/L | 29 | 132 (129–134) | 303 | 132 (130–134) | 0.5 |
| Sodium (indirect potentiometry), mEq/L | 23 | 136 (134–137) | 339 | 135 (133–137) | 0.2 |
| Ionized Calcium, mEq/L | 29 | 1.2 (1.2–1.4) | 276 | 1.2 (1.2–1.4) | 0.9 |
| Glycemia, mg/L | 52 | 108 (94–122) | 641 | 106 (96–120 | 0.7 |
| Albumin, g/dl | 23 | 4.5 (4–5) | 337 | 4.5 (4–5) | 0.3 |
ED, emergency department; NoM, number of measurements; RFS, recurrent febrile seizures.