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. 2024 Mar 4;15:1344058. doi: 10.3389/fendo.2024.1344058

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Copyright © 2024 Liu, Wang, Feng, Ma and Liu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Tumor Mutation Burden and Immune Microenvironment Analysis. (A, B) Comparative plots of tumor mutation burden across the two clusters. (C) Plot showing higher tumor mutation burden in Cluster A compared to Cluster B. (D) Immune microenvironment scores (stromal, immune, and ESTIMATE scores) comparison between the clusters. (E) Analysis of immune cell infiltration showing a higher degree in Cluster A. (F) TIDE score analysis indicating a higher potential for immune escape in Cluster A. *, p<0.05; ***, p<0.001.