Table 4.

Cox regression analysis for outcomes in DKD.

Factors	Univariable		Multivariable model a
	HR(95% CI)	P value	HR(95% CI)	P value
Sex
male	1.0		1.0
female	0.83(0.41,1.69)	0.614	0.57(0.27,1.17)	0.124
Age(years)
<65	1.0		1.0
≥65	1.15(0.74,2.92)	0.270	1.51(0.76,2.99)	0.243
Serum SLPI(ng/mL)
low expression group	1.0		1.0
high expression group	2.95(1.55, 5.62)	0.001	2.95(1.55, 5.60)	0.001
24h UTP(mg/24h)
<3500mg	1.0		1.0
≥3500mg	3.85(2.09, 7.06)	<0.001	3.02(1.66, 5.52)	<0.001
HGB(g/dl)
≥13g	1.0		1.0
<13g	2.65(1.27,5.53)	0.010	3.18(1.49, 6.80)	0.003
Alb(g/L)
≥30g	1.0		1.0
<30g	2.19(1.12,4.29)	0.022	2.19(1.12, 4.28)	0.021
Urea(mmol/L)
<7.1	1.0		1.0
≥7.1	9.59(2.29, 40.26)	0.002	8.27(1.96, 34.93)	0.004

^aEach risk factor (age, serum SLPI, 24h UTP, HGB, Alb, Urea) has been adjusted for the other factors.