TABLE 1.
Characteristics of included studies related the PCOS and IBS.
| Author, year, reference | Study design | Participants | PCOS diagnosis criteria | IBS diagnosis criteria | Findings | Quality score | |||
|---|---|---|---|---|---|---|---|---|---|
| Selection | Comparability | Exposure | Total | ||||||
| Dursun et al. (2018) [19] | Case–control |
Patients with PCOS (n = 54) Controls (n = 53) |
Revised 2003 Rotterdam criteria | Rome III criteria | Prevalence of IBS was 39% in PCOS patients vs 19% in control | 2 | 1 | 2 | 5 |
| Mathur et al. (2010) [20] | Case–control |
Patients with PCOS (n = 36) Controls (n = 29) |
NIH 1990 | Bowel‐related questions | Prevalence of IBS was 41.7% in PCOS patients vs 10.3% in control | 4 | — | 2 | 6 |
| Kałużna et al. (2022) [6] | Case–control |
Patients with PCOS (n = 133) Controls (n = 72) |
ESHRE guideline | Rome IV criteria | Prevalence of IBS was 24% (32/133) in PCOS patients vs. 21% in control (15/72) (p = 0.60) | 3 | 2 | 3 | 8 |
| Bazarganipour et al. (2020) [14] | Case–control |
Patients with PCOS (n = 101) Controls (n = 100) |
Rotterdam diagnostic criteria | Rome III criteria | IBS symptoms were higher in PCOS (20.7%) than control group (11%) (p = 0.05). | 3 | — | 3 | 6 |
| Tseng et al. (2020) [17] | Case–control |
Patients with PCOS (n = 431) Controls (n = 259) |
Rotterdam diagnostic criteria | Rome III criteria | Women with PCOS were more likely to have IBS (10.7% vs. 5.8%, p = 0.029) and obesity (29% vs. 4%, p < 0.001) than healthy volunteers. Mixed‐type IBS (IBS‐M) was the most common subtype (74%) among patients with PCOS and IBS. | 3 | — | 3 | 6 |
| Naziye Gürkan et al. (2022) [7] | Case–control | Women with PCOS (n = 38) and control group (n = 34) | Rotterdam Criteria | Roma IV | IBS prevalence was similar in PCOS (52%) and the control group (50%). | 3 | — | 2 | 5 |
Abbreviations: ESHRE, European Society of Human Reproduction and Embryology; IBS, irritable bowel syndrome; NIH, National Institutes of Health; PCOS, polycystic ovary syndrome.