Figure 2.

Distribution of RSV and RV-specific IgG levels in children (EGEA1, n=531) and adults (EGEA2, n=1241). Shown are IgG levels expressed as fluorescence intensity values (FI: y-axes) to RSV-G protein and VP1 N terminal peptides summed to represent RV-A, RV-B and RV-C species. Summary RV-A, RV-B and RV-C variables were calculated by the sum of IgG responses to 18, 9 and 10 specific peptides respectively, as listed in Supplementary Table S1 . Data are shown as box plots (EGEA1: orange box plots; EGEA2: blue box plots). The lower and upper horizontal lines (hinges) correspond to the first and third quartiles (the 25th and 75th) percentiles. The horizontal line between the first and the third quartile correspond to the median. The upper whisker (vertical line) extends from the hinge to the largest value no further than 1.5*IQR from the hinge (where IQR is the inter-quartile range, or distance between the first and third quartiles). The lower whisker (vertical line) extends from the hinge to the smallest value at most 1.5*IQR of the hinge. Data beyond the end of the whiskers are called "outlying" points and are plotted individually. RSV, respiratory syncytial virus; RV, rhinovirus; EGEA, Epidemiological study on the Genetics and Environment of Asthma.