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. 2024 Mar 4;10(6):e27511. doi: 10.1016/j.heliyon.2024.e27511

Table 2.

Demographic, and obstetric characteristics of parturients who experienced inadvertent dural puncture or PDPH, versus those who did not.

Characteristics Inadvertent dural puncture or PDPH (n = 94) No inadvertent dural puncture or PDPH (n = 26,301) Unadjusted OR (95%CI) P-value
Age (years) 30.7 ± 4.5 30.9 ± 4.8 0.99 (0.95–1.03) 0.6618
Race 0.056a
Chinese 40 (42.6%) 12,078 ± 45.9 Reference
Malay 25 (26.6%) 6,026 ± 22.9 1.25 (0.76–2.07) 0.378
Indian 17 (18.1%) 2,864 ± 10.9 1.79 (1.02–3.17) 0.044
Others 12 (12.7%) 5,333 ± 20.3 0.68 (0.36–1.30) 0.241
Weight (kg) 71.8 ± 15.3 69.2 ± 13.7 1.01 (1.00–1.03) 0.067
Height (cm) 160.0 ± 10.0 160.0 ± 10.0 0.60 (0.01–25.23) 0.789
BMI (kg.m−2) 28.5 ± 5.7 27.4 ± 5.1 1.04 (1.00–1.07) 0.043
ASA physical statusb 0.173a
 I 63 (67.0%) 17,006 (64.7%) Reference
 II 27 (28.7%) 8,813 (33.5%) 0.83 (0.53–1.30) 0.410
 III 4 (4.3%) 482 (1.8%) 2.24 (0.81–6.18) 0.119
Parity
Nulliparous 58 (61.7%) 15,787 (60.0%) 1.07 (0.71–1.63) 0.740
Multiparous 36 (38.3%) 10,520 (40.0%) 0.93 (0.61–1.14) 0.737
Direct morbidity (e.g. PIH) 2 (2.1%) 216 (0.8%) 2.63 (0.64–10.72) 0.179
Indirect morbidity (e.g. CVS problems) 1 (1.1%) 40 (0.6%) 7.06 (0.96–51.90) 0.055
Labour onset
Spontaneous 43 (45.7%) 14,204 (54%) 0.72 (0.48–1.08) 0.110
Prostin usec 34 (36.2%) 7,605 (28.9%) 1.39 (0.91–2.12) 0.123
Artificial rupture of membranes 18 (19.1%) 4,995 (19%) 1.00 (0.60–7.70) 0.971
Number of Prostin tablets used 0.4 ± 0.9 0.3 ± 0.6 1.32 (1.03–1.69) 0.029
Cervical dilation at time of procedure (cm) 3.6 ± 1.1 3.5 ± 1.0 1.15 (0.94–1.39) 0.173

Values are mean ± SD or number (proportion).

ASA, American Society of Anesthesiologists. BMI, body mass index. CI, confidence interval. CVS, cardiovascular system. PDPH, post-dural puncture headache. OR, odds ratio. PIH, pregnancy-induced hypertension. SD, standard deviation.

a

Type 3 p-value.

b

Our institution defines ASA physical status score as I: healthy parturient; II: parturient with mild systemic disease; III: parturient with severe systemic disease; IV: parturient with severe systemic disease that is a constant threat to life. There was no ASA physical status IV parturients included in our dataset.

c

Prostaglandin E2 suppository.