Fig. 4.

Effect of DIO on colon histological alterations (H & E; x200) in normal control (A), 4% (w/v) DSS-induced colitis (B), DSS-induced colitis treated with SSZ (200 mg/kg) (C), DSS-induced colitis treated with DIO at doses of 100 mg/kg (D), and 200 mg/kg (E). Black arrows indicated mucosal epithelial lining cells, red arrows indicated linear crypts, yellow arrows indicated lamina propria, and green arrows indicated muscle layer. DSS: dextran sulfate sodium; SSZ: sulfasalazine; DIO: diosmin. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)