TABLE 2.

β-chemokine production and HIV-1 status of T-cell clones from HIV-1-infected individuals

Clonea	CD4/CD8	HIV statusb		β-Chemokine (pg/ml)
		DNA	p24	RANTES	MIP-1α	MIP-1β
NP1-1	CD4	+	−	5,510	7,940	15,984
NP1-2	CD4	−	−	13,794	21,747	18,984
NP1-3	CD4	−	−	38,053	21,915	18,912
NP1-4	CD4	−	−	27,484	19,866	20,634
NP1-5	CD4	−	−	12,520	20,403	20,280
NP1-6	CD4	−	−	13,666	20,319	19,356
NP1-7	CD4	−	−	6,599	19,983	19,695
NP2-1	CD4	−	−	3,733	5,080	20,616
NP2-4	CD4	−	−	21,435	6,715	17,865
NP2-5	CD4	−	−	18,187	9,755	13,731
NP2-2	CD8	NAc	NA	0	207	3,532
NP2-3	CD8	NA	NA	10,220	21,560	39,888
AD1-1d		+	+	0	0	0
AD1-3d		+	+	0	0	0
AD1-6	CD4	−	−	0	0	4,143
AD1-8d		+	+	0	276	2,256
AD1-12	CD4	−	−	0	0	0
AD1-13	CD4	−	−	0	0	1,985
AD1-15	CD4	−	−	0	0	0
AD1-18d		+	+	0	0	3,534
AD1-19	CD4	−	−	0	0	0
AD1-23	CD4	−	−	0	0	0
AD1-30	CD4	−	−	0	0	0
AD1-27	CD8	NA	NA	20,780	0	41,400
AD1-28	CD8	NA	NA	15,860	34,328	44,184
AD2-1	CD4	−	−	0	0	618
AD2-2	CD4	−	−	0	0	0
AD2-4	CD4	−	−	0	0	0
AD2-8	CD4	−	−	0	0	0
AD2-3	CD8	NA	NA	10,700	39,200	38,624
AD2-7	CD8	NA	NA	12,325	41,480	44,184
MHCD4	CD4	NA	NA	0	0	0
CHCD4	CD4	NA	NA	8,770	36,768	34,576
KRCD8	CD8	NA	NA	15,285	36,616	40,392

^aT-cell clones are as described in Table 1. MHCD4 and CHCD4 are CD4⁺ T-cell clones, and KRCD8 is a CD8⁺ HVS-immortalized T-cell clone from normal donors (25). 

^bHIV-1 DNA is by PCR, and p24 is by ELISA. 

^cNA, not applicable. 

^dThis HIV-1-producing clone was surface-CD4 negative but expressed CD4 mRNA (data not shown).