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. 2024 Feb 5;12:RP88087. doi: 10.7554/eLife.88087

Table 1. Estimates of total number of origins by different criteria (estimates from all but first two rows rely on candidate MCM binding sites [CMBSs] from this report).

Criterion Estimate of number of origins
SGD classification 354 (343 of which map unambiguously)
OriDB classification 829 (410 confirmed, 216 likely, 203 dubious)
Generation of ssDNA in HU 1600
BrdU incorporation 1400
Nucleosome-free regions 5000
Transition from mostly intergenic to mostly genic 6000
Transition from low transcription genic to high transcription genic 5000
ACS motif 6000
GC skew 6000