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. 2024 Feb 24;14(5):1873–1885. doi: 10.7150/thno.90627

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Spatial analysis of proliferating cancer cells and immune infiltrate in BC samples. (A) Histological annotation of two representative BC samples (other samples are shown in Figure S14), and estimation of highly proliferative regions (S+G2M phases) (higher panels); actively cycling cancer cells and two immune populations (macrophages and CD8⁺ T cells) (middle and lower panels). The heat map shows spatial correlation between these four populations. (B) Correlation analysis for the four selected cell populations in the other eight BC samples.