Table 1. Anthropometric and biochemical analyses in study participants.
| Variable | Controls baseline(n=10) | PCOS baseline(n=10) | Controls vs. PCOS(p-value) | PCOS treatment(n=10) | Baseline vs. treatment(p-value) |
|---|---|---|---|---|---|
| Age (years) | 31.2±4.8 | 30.1±5.1 | 0.60 | ||
| Weight (kg) | 88.2±11.0 | 88.6±15.6 | 0.82 | 89.0±14.9 | 0.33 |
| BMI (kg/m2) | 30.5±3.7 | 30.5±4.1 | 0.88 | 30.7±4.0 | 0.32 |
| Ferriman-Gallwey score | 2.1±1.7 | 7.7±4.5 | 0.003 | 9.2±6.0 | 0.48 |
| Testosterone (pg/ml) | 258±77 | 476±211 | 0.004 | 347±220 | 0.012 |
| Insulin (mU/ml) | 8.2±3.5 | 11.4±8.5 | 0.47 | 8.5±4.8 | 0.11 |
| Glucose (mmol/l) | 5.2±0.3 | 4.8±0.4 | 0.044 | 4.8±0.3 | 0.67 |
| HOMA-IR | 1.92±0.96 | 2.75±2.00 | 0.41 | 1.89±1.33 | 0.037 |
| Hemoglobin A1c (mmol/mol) | 31.5±2.6 | 31.7±2.7 | 1.00 | 30.5±2.9 | 0.035 |
| Triglycerides (mmol/l) | 0.71±0.18 | 1.11±0.58 | 0.076 | 1.01±0.58 | 0.066 |
Data are presented as mean ± SD. Differences between PCOS and controls were analyzed by Mann-Whitney U test. Wilcoxon signed-rank test was used to analyze changes between measurements at baseline and after 5 weeks of treatment. p-value < 0.05 was considered significant.