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(A) The E1E2 complex of CHIKV. The structure is represented as ribbons, with green indicating the E2 glycoprotein, blue indicating the E1 glycoprotein, and red indicating the fusion loop. The amino acid residues involved in the intramolecular interactions between E1 and E2 are shown as sticks. (B) The MXRA8 receptor (magenta ribbon) binds to the E1E2 complex. The transmembrane part of E1E2 is included (“TM”) (PDB id: 6JO8).223
