Figure 5.

Crystal structure of the HP23L-gp41 complex (PDB id 5YB3) (A). Intermolecular interactions stabilizing the complex (B) and the structure of the L-T hook (C). gp41 is shown as a blue ribbon or as a solvent-accessible surface colored by interpolated charge (blue–positive, gray–neutral, red–negative). The HP23L peptide is shown as an orange ribbon or in stick representation colored according to atom types, and noninteracting side chains are hidden for clarity. Intermolecular interactions are shown as dashed lines in the same color as in Figure 1.