Figure 7.

Mode of binding of temsavir to gp120: the temsavir-gp120 complex (A) and closeup of the binding cavity of gp120 with interactions between temsavir and the target (PDB id 5U7O). gp120 is shown as a cyan ribbon with β20-β12 and CD4-binding loops colored red and yellow, respectively. Interacting residues (B) are shown in stick representation colored according to atom type and carbon atom color that matches the parent chain color. Temsavir is shown as space-filling balls. Intermolecular interactions are shown as dashed lines in the same color as in Figure 1.