Fairbank 2005.
Methods | RCT conducted in the UK | |
Participants | Patients referred to surgical departments of 15 hospitals with age 18‐55, LBP >1 year, surgeon unsure if surgery or rehab more suitable. 349 patients randomised, 50.7% female, average age not reported, mean duration of pain 8 years | |
Interventions |
MBR (Rehabilitation): 5 days/week for 3/52 plus 1 follow‐up session. Stretching, strengthening, stabilisation, cardiovascular endurance, hydrotherapy. CBT approach; pacing, addressing unhelpful beliefs and fears Surgery (Surgery): Spinal stabilisation surgery |
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Outcomes | Pain (SF‐36 bodily pain), Disability (ODI), General Health (SF‐36) Follow‐ups: LT (2 years) | |
Notes | Subgroup analyses: Mid‐intensity intervention, Low baseline symptom intensity (<60% of maximum scale score) | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | Pg.2 Treatment allocation. "Randomisation was generated centrally by computer program" |
Allocation concealment (selection bias) | Unclear risk | Unclear |
Blinding of participants | High risk | Not possible |
Blinding of clinicians | High risk | Not possible |
Blinding of outcome assessment (detection bias) All outcomes | High risk | Not possible; patient reported outcome |
Incomplete outcome data (attrition bias) All outcomes | Low risk | Flow chart. 12‐month follow‐up rate 89% |
Intention to treat analysis | Low risk | pg.2 Statistical Methods. "We carried out an intention to treat analysis" |
Selective reporting (reporting bias) | Unclear risk | No protocol |
Comparability of groups at baseline | Low risk | Table 1 |
Compliance | Unclear risk | Not stated |
Cointerventions | Low risk | Table 3 (Rivero‐Arias). Other resource usage comparable between groups |
Timing of assessment | Low risk | pg.2 Outcome Measures. "We assessed outcomes at baseline and 6, 12, and 24 months from randomisation" |