Table 3. Targeted RNA-seq of Peromyscus leucopus blood in 12 hr experiment with LPS dose of 1 µg/g.
Table 3—source data 1. Targeted RNA-seq of blood of P. leucopus 12 h after treatment with LPS (1 µg/g) or saline.
elife-90135-table3-data1.xlsx (11.2KB, xlsx)
| Gene (alternative name) | Control (n=3) mean (95% CI)* | LPS (n=3) mean (95% CI)* | Fold change | FDR p value† |
|---|---|---|---|---|
| Akt1 | 220 (12–4202) | 514 (321–825) | 2.3 | 0.05 |
| Akt2 | 145 (97–217) | 336 (236–478) | 2.3 | 0.04 |
| Arg1 | 146 (58–367) | 2812 (273–28,925) | 19 | 0.018 |
| Cd14 | 82 (12–569) | 914 (161–5197) | 11 | 0.05 |
| Cd69 | 165 (87–310) | 68 (14–329) | 0.42 | 0.15 |
| ERV env | 25 (3–242) | 40 (7–224) | 1.6 | 0.86 |
| ERV gag-pol | 3085 (132–14,695) | 2768 (533–1278) | 0.9 | 0.66 |
| Fcgr3 | 40 (25–66) | 841 (533–1278) | 21 | 0.008 |
| Gapdh | 7176 (3504–15,142) | 23811 (5827–97,306) | 3.3 | 0.07 |
| Gbp4 | 97 (6–1551) | 439 (33–5819) | 4.5 | 0.05 |
| Ifit1 | 367 (51–2663) | 1373 (374–5047) | 3.7 | 0.05 |
| Ifng | 0 (0–0) | 0 (0–0) | . | . |
| Il1b | 258 (18–3652) | 1432 (183–11,220) | 5.6 | 0.1 |
| Irf7 | 121 (93–157) | 11405 (530–245,616) | 94 | 0.003 |
| Isg15 | 429 (184–1001) | 19505 (11140–34,152) | 45 | 0.005 |
| Mx2 | 157 (73–341) | 1310 (323–5315) | 8.3 | 0.04 |
| Nos2 | 0 (0–0) | 0 (0–0) | . | . |
| Oas1 | 65 (31–138) | 1458 (367–5795) | 22 | 0.03 |
| Rigi (Ddx58) | 38 (3–504) | 173 (35–845) | 4.5 | 0.07 |
| Saa3 | 2 (0–250) | 6683 (1494–29,896) | 3372 | 0.03 |
| Slpi | 6 (1-46) | 779 (326–1864) | 123 | 0.03 |
| Sod2 | 180 (54–607) | 3406 (698–16,633) | 19 | 0.03 |
*
Mean unique reads for given gene normalized for reads for Ptprc (Cd45) gene for a sample. The 95% confidence intervals (CI) are asymmetric. Actual [gene]/Ptprc ratios are x 10–3 (Source data 1).
†
FDR, false discovery rate p value.