Table 3. Simulation parameters for Figure 1—figure supplement 1.

Shading has been added to highlight which simulation parameters were changed, with respect to the reference parameters used in Figure 1. The GDP fold weaker values are the fold change between the GTP- and GDP-type interaction.

Figure 1—figure supplement 3	change	kon(µM–1 s–1)	KDlongGTP(µM)	KDcornerGTP(µM)	KDlongGDP(µM)	KDcornerGDP(µM)	GDPlong fold weaker	GDPcorner fold weaker	Tubulin (µM)
Figure 1—figure supplement 3A	GDP weakening	1.0	100	0.1	3x106	3000	30,000	30,000	1
Figure 1—figure supplement 3A	GDP weakening	1.0	100	0.1	3x105	300	3,000	3,000	1
Figure 1—figure supplement 3	GDP weakening	1.0	100	0.1	3x104	30	300	300	1
Figure 1—figure supplement 3	KDlong	1.0	1000	0.1	3x106	300	3000	3000	1
Figure 1—figure supplement 3	KDlong	1.0	100	0.1	3x105	300	3000	3000	1
Figure 1—figure supplement 3	KDlong	1.0	10	0.1	3x104	300	3000	3000	1
Figure 1—figure supplement 3	KDcorner	1.0	100	0.5	3x105	1500	3000	3000	1
Figure 1—figure supplement 3	KDcorner	1.0	100	0.1	3x105	300	3000	3000	1
Figure 1—figure supplement 3	KDcorner	1.0	100	0.02	3x105	60	3000	3000	1