Table 4. Calculated on-rates and off-rates for simulations in Figure 1—figure supplement 1.
On-rate is calculated using the biochemical kon and the concentration of tubulin [µM]. Off-rate is calculated using the biochemical kon and the dissociation constant KD. All simulations in Figure 1—figure supplements 2 and 3 use the same biochemical kon for plus-end and minus-end simulations, as was done in Figure 1. Shading highlights which off-rates changed, with respect to the original values in Figure 1.
| Figure 1—figure supplement 3 | On-rate (s–1) | kofflong GTP (s–1) | koffcorner GTP (s–1) | kofflong GDP (s–1) | koffcorner GDP (s–1) | Tubulin (µM) |
|---|---|---|---|---|---|---|
| Figure 1—figure supplement 3A | 1 | 100 | 0.1 | 3x106 | 3000 | 1 |
| Figure 1—figure supplement 3A | 1 | 100 | 0.1 | 3x105 | 300 | 1 |
| Figure 1—figure supplement 3A | 1 | 100 | 0.1 | 3x104 | 30 | 1 |
| Figure 1—figure supplement 3B | 1 | 1000 | 0.1 | 3x106 | 300 | 1 |
| Figure 1—figure supplement 3B | 1 | 100 | 0.1 | 3x105 | 300 | 1 |
| Figure 1—figure supplement 3B | 1 | 10 | 0.1 | 3x104 | 300 | 1 |
| Figure 1—figure supplement 3C | 1 | 100 | 0.5 | 3x105 | 1500 | 1 |
| Figure 1—figure supplement 3C | 1 | 100 | 0.1 | 3x105 | 300 | 1 |
| Figure 1—figure supplement 3C | 1 | 100 | 0.02 | 3x105 | 60 | 1 |