Author response image 2. Three-dimensional distribution of sodium ions around the nucleosome determined from all-atom explicit solvent simulations.

Darker blue colors indicate higher sodium density and high density of sodium ions around the DNA is clearly visible. The crystallographically identified acidic patch has been highlighted as spheres on the surface of the histone core and a high level of sodium condensation is observed around these residues. Figure reproduced from [2].

© 2009, American Chemical Society

This figure is reproduced with permission from Figure 7 in Materese CK, Savelyev A, Papoian GA (2009) Counterion Atmosphere and Hydration Patterns near a Nucleosome Core Particle. J. Am. Chem. Soc. 131:15005–15013.. It is not covered by the CC-BY 4.0 license and further reproduction of this figure would need permission from the copyright holder.