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. 2024 Feb 29;15:1301976. doi: 10.3389/fpsyt.2024.1301976

Table 2.

Alcohol and substance use characteristics of cases and controls.

Variable Patient Type p-value2
control, N = 3,9401 case, N = 4,4151
Tobacco Products (cigarettes, chewing tobacco, cigars, etc.), n (%) 682 (17.3) 1,387 (31.4) <0.001
Tobacco Products: How often have you used these substances in the past 3 months?, n (%) <0.001
 None 413 (60.6) 712 (51.3)
 None frequent 86 (12.6) 235 (16.9)
 Frequent 183 (26.8) 440 (31.7)
Alcoholic beverages (beer, wine spirits, homebrew, etc), n (%) 1,811 (46.0) 1,990 (45.1) 0.41
Alcohol Products: How often have you used these substances in the past 3 months?, n (%) <0.001
 None 947 (52.3) 1,358 (68.2)
 None frequent 636 (35.1) 376 (18.9)
 Frequent 228 (12.6) 256 (12.9)
Khat products, n (%) 485 (12.3) 976 (22.1) <0.001
Khat Products: How often have you used these substances in the past 3 months?, n (%) 0.068
 None 261 (53.8) 578 (59.2)
 None frequent 124 (25.6) 240 (24.6)
 Frequent 100 (20.6) 158 (16.2)
Cannabis (marijuana, pot, grass, hash, etc.), n (%) 454 (11.5) 991 (22.4) <0.001
Cannabis Products: How often have you used these substances in the past 3 months?, n (%) 0.094
 None 291 (64.1) 692 (69.8)
 None frequent 91 (20.0) 169 (17.1)
 Frequent 72 (15.9) 130 (13.1)
Other over-the-counter meds (antihistamines, cough syrups), n (%) 88 (2.2) 46 (1.0) <0.001
Other Over-the-Counter Meds: How often have you used these substances in the past 3 months?, n (%) 0.014
 None 36 (40.9) 31 (67.4)
 None frequent 41 (46.6) 12 (26.1)
 Frequent 11 (12.5) 3 (6.5)
Sedatives or Sleeping Pills (Valium, mandrax/methaqualone, sere-pax, Rohypnol, etc.), n (%) 44 (1.1) 138 (3.1) <0.001
Opioids (heroin, morphine, oxycontin, methadone, codeine, etc.), n (%) 28 (0.7) 144 (3.3) <0.001
Opioids Products: How often have you used these substances in the past 3 months?, n (%) <0.001
 None 10 (35.7) 128 (88.9)
 None frequent 3 (10.7) 4 (2.8)
 Frequent 15 (53.6) 12 (8.3)
Any substance use, n (%) 1,986 (50.4) 2,348 (53.2) 0.011

1Median (IQR) or Frequency (%).

2Pearson’s Chi-squared test; Fisher’s exact test.