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. 2024 Jan 15;12:RP91469. doi: 10.7554/eLife.91469

Table 1. Site-specific primary triage and treatment protocols Biopsy and treatment protocols.

Site Primary Screening Test Triage method Staff taking biopsies Biopsy Instrument Treatment threshold Primary Treatment
Dominican Republic ScreenFire HPV, Cytology Colposcopy Gynecologists Biopsy forceps CIN2+ +biopsy Ablation or LLETZ
Malawi ScreenFire HPV VIA Nurses Softbrush VIA-positive Ablation or LLETZ
Nigeria ScreenFire HPV Colposcopy General Doctors,
Gynecologists,
GYN oncologists
Biopsy forceps HPV-positive Ablation or LLETZ
Brazil ScreenFire HPV Conventional cytology, liquid-based cytology, and colposcopy Gynecologists Biopsy forceps CIN2 + biopsy or high-grade colpo impression LLETZ
Cambodia ScreenFire HPV Colposcopy (mobile colposcope) Nurse midwives, General Doctors,
Gynecologists
Softbrush VIA-positive or
HPV16,18/45 positive
Ablation or LLETZ
Eswatini ScreenFire HPV & VIA VIA Nurse midwives Softbrush VIA-positive Ablation
El Salvador ScreenFire HPV, Cytology, CareHPV Colposcopy and VAT General Doctors Biopsy forceps HPV-positive Ablation
Tanzania ScreenFire HPV VIA Gynecologists, nurses, nurse midwives Biopsy forceps, Softbrush VIA-positive Ablation
Honduras ScreenFire HPV Colposcopy and VAT Nurse midwives, General Doctors, Biopsy forceps VIA-positive Ablation