Appendix 1—table 1. RNA and DNA oligonucleotide primers used for siRNA knockdown, RT-qPCR, and genotyping experiments.

Mouse Esr2 siRNA	CAAGUGUUACGAAGUAGGAdT
Mouse Col11a1 siRNA	GAAAGAAGGUGCAAAGGGUdT
Mouse Mmp3 F	CTCTGGAACCTGAGACATCACC
Mouse Mmp3 R	AGGAGTCCTGAGAGATTTGCGC
Mouse Col11a1 F	AGGAGAGTTGAGAATTGGGAATC
Mouse Col11a1 R	TGGTGATCAGAATCAGAAGTT
Mouse Col11a2 F	CTCATCTTCCTGCATCAGAC
Mouse Col11a2 R	ACTTGGAAAGCGAGGTCCT
Mouse Adgrg6 F	AGAGGATGGACTGAGGCTGTGT
Mouse Adgrg6 R	CCAGGCTTGTTTGGACATGGTTG
Mouse Sox6 F	GCATAAGTGACCGTTTTGGCAGG
Mouse Sox6 R	GGCATCTTTGCTCCAGGTGACA
Mouse Mmp14 F	GCCTTCTGTTCCTGATAA
Mouse Mmp14 R	CCATCCTTCCTCTCGTAG
Mouse Pax1 F	AACCAGCACGGAGTATACAGC
Mouse Pax1 R	TGTAAGCTACCGAGTGCATCC
Mouse Esr2 F	GGTCCTGTGAAGGATGTAAGGC
Mouse Esr2 R	TAACACTTGCGAAGTCGGCAGG
Mouse Gapdh F	CATCACTGCCACCCAGAAGACTG
Mouse Gapdh R	ATGCCAGTGAGCTTCCCGTTCAG
Rat Sfrp2 F	CGTGAAACGGTGGCAGAAG
Rat Sfrp2 R	CGGATGCTGCGGGAGAT
Rat Krt19 F	AAGACACACTGGCAGAAACG
Rat Krt19 R	GATTCTGCCGCTCACTATCA
Rat Mmp12 F	TTGGCCATTCCTTGGGGCTGC
Rat Mmp12 R	TGTTGGTGGCTGGACTCCCAGG
Mouse Pax1 F (Figure 5)	CCGCACATTCAGTCAGCAAC
Mouse Pax1 R (Figure 5)	CATCTTGGGGGAGTAGGCAG
Mouse Col11a1 F (Figure 5)	CACAAAACCCCTCGATAGAAGTG
Mouse Col11a1 R (Figure 5)	CCTGTGATCAGGAACTGCTGAA
Mouse Adgrg6 F (Figure 5)	TCCTGTCCATCTCTGGCTCA
Mouse Adgrg6 R (Figure 5)	CACAAGACAGAGCTGCTCCA
Mouse Sox6 F (Figure 5)	TGCGACAGTTCTTCACTGTGG
Mouse Sox6 R (Figure 5)	CGTCCATCTTCATACCATACG
Mouse β-Actin F (Figure 5)	GGCACCACACCTTCTACAATG
Mouse β-Actin R (Figure 5)	GGGGTGTTGAAGGTCTCAAAC
Pax1-genotyping F	CAGAACCTGGAATGCTGTGCTC
Pax1-genotyping R	AAAGGGTTGCAGTGCCTTCAC