Table 2.
Imaging characteristics of bone in patients with CNO and controls on [18F]NaF-PET/CT.
| CNO (n = 43) | Controls (n = 16) | OR (95% CI) | p | |
|---|---|---|---|---|
| Clavicle Sclerosis Bilateral Hyperostosis Bilateral Increased [18F]NaF uptake Bilateral |
30 (70) 14 (33) 20 (47) 8 (19) 31 (72) 17 (40) |
7 (44) 0 (0) 0 (0) 0 (0) 8 (50) 1 (6) |
3 (0.9–10) 20 (0.9–424) 35 (2–761) 9 (0.4–217) 3 (0.8–8) 10 (1–81) |
.072 .058 .022 .161 .116 .034 |
| Manubrium Sclerosis Hyperostosis Increased [18F]NaF uptake |
33 (77) 32 (74) 30 (70) |
1 (6) 0 2 (13) |
50 (6–422) 102 (5–2280) 20 (4–104) |
< .001 <.001 .004 |
| Costae 1–2 Sclerosis/hyperostosis Bilateral Increased [18F]NaF uptake Bilateral |
34 (79) 29 (67) 35 (81) 25 (58) |
1 (6) 1 (6) 9 (56) 6 (38) |
57 (7–488) 31 (4–259) 3 (0.9–12) 2 (0.7–8) |
<.001 .002 .055 .163 |
| Spine (involved in n = 8 patients) Sclerosis/hyperostosis Increased [18F]NaF uptake |
8 (100) 7 (88) |
1 (6) 2 (13) |
3 (0.4–30) 2 (0.4–6) |
.256 .545 |
Abbreviations: CNO, chronic nonbacterial osteitis; OR, odds ratio; [18F]NaF, sodium fluoride-18; [18F]NaF-PET/CT, sodium fluoride-18 positron emission tomography/computed tomography.
Data are presented as n (%).