Table 3.
Imaging characteristics of soft tissue and joints in patients with CNO and controls on [18F]NaF-PET/CT.
| CNO (n = 43) | Controls (n = 16) | OR (95% CI) | p | |
|---|---|---|---|---|
| Sternoclavicular joint(s) Erosion Calcification Increased [18F]NaF uptake |
14 (32) 0 (0) 12 (28) |
3 (19) 1 (6) 2 (13) |
2 (0.5–9) 0.8 (0.4–1) 3 (0.5–14) |
.304 .362 .229 |
| Manubriosternal joint Erosion Ankylosis (noncongenital) Increased [18F]NaF uptake |
14 (33) 4 (9) 15 (35) |
1 (6) 0 (0) 2 (13) |
7 (0.9–60) 4 (0.2–115) 4 (0.8–19) |
.068 .373 .107 |
| Costoclavicular ligament(s) Calcification/ankylosis Increased [18F]NaF uptake |
25 (58) 23 (54) |
1 (6) 0 (0) |
21 (3–172) 48 (2–1022) |
.005 .014 |
| Costosternal joint(s) 1–3 Sclerosis/hyperostosis Increased [18F]NaF uptake |
33 (77) 34 (79) |
1 (6) 8 (50) |
57 (7–488) 3 (1–12) |
<.001 .055 |
| Costochondral transition(s) 1–3 Sclerosis and/or hyperostosis Increased [18F]NaF uptake |
13 (31) 13 (30) |
0 (0) 2 (13) |
20 (0.9–424) 3 (0.6–15) |
.058 .179 |
Abbreviations: CNO, chronic nonbacterial osteitis; OR, odds ratio; [18F]NaF, sodium fluoride-18; [18F]NaF-PET/CT, sodium fluoride-18 positron emission tomography/computed tomography.
Data are presented as n (%).