Table 2. Evolutionary parameters appearing in the analytical derivations of the expected VAF distribution in the Moran and pure-birth models.

Symbol	Description
${\displaystyle N}$	Total number of cells
${\displaystyle k}$	Abundance or number of cells < N
${\displaystyle V_k(t)}$	Number of mutations with abundance k
${\displaystyle P_k}$	Likelihood for a mutation with abundance k to increase or decrease
${\displaystyle C_k(t)}$	The average number of mutations with abundance k that increase or decrease
${\displaystyle \frac{d{V}_k(t)}{dt}}$	Average change of ${\displaystyle V_k(t)}$ per time step
${\displaystyle \mu }$	Mutation rate per daughter cell