In vitro study % enzyme inhibition and IC50 of isolated compounds.
| Compounds | % Inhibition | IC50 ± SEM (μM) |
|---|---|---|
| 7 | 81.57 | 1.22 ± 0.43 |
| 2 | 82.05 | 1.30 ± 0.28 |
| 14 | 80.42 | 1.95 ± 0.31 |
| 15 | 80.00 | 2.78 ± 0.24 |
| 4 | 82.73 | 3.87 ± 0.24 |
| 5 | 77.52 | 4.73 ± 0.22 |
| 11 | 72.89 | 5.20 ± 0.14 |
| 12 | 78.21 | 5.92 ± 0.25 |
| 10 | 76.57 | 6.68 ± 0.11 |
| 1 | 82.32 | 1.02 ± 0.35 |
| Synthesized compound | 69 | 8.03 ± 0.19 |
| 6 | 71.52 | 5.03 ± 0.12 |
| 9 | 13.42 | — |
| 13 | 63.47 | 6.24 ± 0.30 |
| 16 | 19.47 | — |
| Standard (thiourea) | 86.73 | 18.61 ± 0.11 |