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. 2024 Mar 18;14(13):9159–9168. doi: 10.1039/d3ra08913d

In vitro study % enzyme inhibition and IC50 of isolated compounds.

Compounds % Inhibition IC50 ± SEM (μM)
7 81.57 1.22 ± 0.43
2 82.05 1.30 ± 0.28
14 80.42 1.95 ± 0.31
15 80.00 2.78 ± 0.24
4 82.73 3.87 ± 0.24
5 77.52 4.73 ± 0.22
11 72.89 5.20 ± 0.14
12 78.21 5.92 ± 0.25
10 76.57 6.68 ± 0.11
1 82.32 1.02 ± 0.35
Synthesized compound 69 8.03 ± 0.19
6 71.52 5.03 ± 0.12
9 13.42
13 63.47 6.24 ± 0.30
16 19.47
Standard (thiourea) 86.73 18.61 ± 0.11