Table 2.

Final selected radiomics features and the significant differences of the medullary thyroid carcinoma patients between lateral cervical lymph node metastases (LCLNM) negative and LCLNM positive. Data are presented as medians with ranges in parentheses

Final radiomics features	LCLNM negative (n=111)	LCLNM positive (n=107)	p-Value
First order statistics
wavelet-HL_firstorder_Median	4.2e-2 (-7.1e-2~0.3)	3.1e-2 (-8.5 e-2~0.1)	<0.001
wavelet-HL_firstorder_Skewness	-2.7e-2 (-14.3~14.4)	0.2 (-10.9~24.1)	0.017
Shape-based features
original_shape2D_MinorAxisLength	145.9 (42.4~550.0)	220.3 (53.1~555.4)	<0.001
GLCM
wavelet-LL_glcm_Imc2	0.98 (0.91~1)	0.98 (0.89~1)	0.042
wavelet-HH_glcm_ClusterProminence	0.5 (0.5~47.4)	0.6 (0.5~19.1)	0.005
wavelet-LL_glcm_ClusterShade	142.8 (-68.4~1303.6)	103.7 (-213.2~1018.4)	0.029
GLSZM
original_glszm_SizeZoneNonUniformity	20.5 (1.9~122.5)	40.7 (3.6~440.9)	<0.001
wavelet-LH_glszm_ZoneEntropy	5.8 (4.3~6.6)	6.0 (4.4~6.6)	<0.001
original_glszm_SmallAreaLowGrayLevelEmphasis	2.8e-02 (0.3e-2~0.1)	3.6e-2 (0.6e-2~0.1)	0.010
waveletLL_glszm_SizeZoneNonUniformity	95.8 (9.8~533.5)	136.8 (9.0~1134.7)	<0.001
NGTDM
wavelet-HH_ngtdm_Strength	7.5e-4 (3.1e-5~0.1)	2.1e-3 (1.9e-5~4.4e-2)	0.001
GLDM
wavelet-HH_gldm_LargeDependenceLowGrayLevelEmphasis	4.6 (0.2~18.6)	2.2 (0.2~19.1)	<0.001