Figure 1.

PREDDICT RCT schedule of treatments and assessments^a. ^aAdapted fromKavakbasi et al., 2023. A, administration of the Oxford Depression Questionnaire (ODQ) assessment; B, collection of peripheral venous blood; R, randomization. Participation in the trial and continued treatment with vortioxetine was optional from week 8. Week 22 and week 35 indicate 3-month follow-up from week 8 and 6-month follow-up from week 8, respectively. Other assessments at all listed time points were performed but are not listed here because they are outside the scope of this publication. For full list and timings of all assessments, see (Fourrier et al., 2018).