TABLE 1.
Sample characteristics a .
| Variable (reporting age (years)) | Missing (n (%)) | Males | Females |
|---|---|---|---|
| Sex (birth) | ‐ | 3992 (49.1) | 4138 (50.9) |
| NETCRF (45 years) | 2150 (26.4) | ||
| (METS) | 11.8 (1.2) | 9.0 (1.3) | |
| kg/ml/min | 41.4 (16.7) | 31.7 (4.6) | |
| Weight (kg) (45 years) | 111 (1.4) | 85 (76.4, 94.4) | 68.2 (60.8, 78.4) |
| Height (cm) (45 years) | 78 (1.0) | 176.1 (6.7) | 162.6 (6.2) |
| BMI (kg/m2) (45 years) | 140 (1.7) | 27.3 (25.0, 30.1) | 25.7 (23.1, 29.7) |
| Resting heart rate (45 years) | 64 (0.8) | 70.4 (11.1) | 72.5 (10.0) |
| Immediate verbal memory (Number of words correctly recalled) (50 years) | ‐ | 6.4 (1.5) | 6.7 (1.5) |
| Verbal fluency (Number of animals mentioned) (50 years) | ‐ | 22.4 (6.4) | 22.4 (6.1) |
| Visual processing speed (Total number of letters scanned) (50 years) | 149 (1.8) | 312 (270, 372) | 325 (284, 400) |
| Delayed verbal memory (Number of words correctly recalled after delay) (50 years) | 53 (0.7) | 5.2 (1.8) | 5.7 (1.8) |
| Social class (birth b ) | ‐ | ||
| Professional/managerial | 799 (20.0) | 794 (19.2) | |
| Skilled non‐manual | 405 (10.2) | 400 (9.7) | |
| Skilled manual | 1888 (47.3) | 1984 (48.0) | |
| Semiskilled/unskilled manual/no male head | 900 (22.6) | 960 (23.2) | |
| Childhood cognitive function (mean reading and maths score) (11 years) | 1037 (12.8) | 17.8 (7.7) | 17.5 (7.2) |
| Educational attainment (33 years) | 917 (11.3) | ||
| No qualifications | 492 (14.1) | 446 (12.0) | |
| CSE/O‐level | 1992 (57.2) | 2256 (60.5) | |
| A‐level | 376 (10.8) | 454 (12.2) | |
| >A‐level | 621 (17.8) | 576 (15.4) | |
| Smoking status (42 years) | 201 (2.5) | ||
| Never | 1766 (45.5) | 1944 (48.0) | |
| Ex‐smoker | 1065 (27.5) | 1001 (24.7) | |
| Current | 1049 (27.0) | 1104 (27.3) | |
| Alcohol consumption frequency (42 years) | 200 (2.5) | ||
| Never | 134 (3.5) | 228 (5.6) | |
| Rarely | 305 (7.9) | 668 (16.5) | |
| Two to four times per month | 1058 (27.3) | 1311 (32.4) | |
| At least twice per week | 2384 (61.4) | 1842 (45.5) | |
| BMI (kg/m2) (42 years) | 422 (5.2) | 25.9 (23.8, 28.4) | 24.0 (21.9, 27.3) |
| Physical activity (42 years) | 202 (2.5) | ||
| ≤3 per month | 1370 (33.8) | 1289 (33.2) | |
| Once per week | 699 (17.3) | 814 (21.0) | |
| Two to three times per week | 867 (21.4) | 854 (22.0) | |
| Four to seven times per week | 1112 (27.5) | 923 (23.8) | |
| Self‐rated health over previous 12 months (42 years) | 199 (2.5) | ||
| Excellent | 1171 (30.2) | 1111 (27.4) | |
| Good | 1848 (47.6) | 1907 (47.1) | |
| Fairly good | 594 (15.3) | 611 (15.1) | |
| Not so good | 268 (6.9) | 421 (10.4) | |
a
Categorical variables summarized as n(%), continuous variables as mean(SD) or median(25th, 75th centile), see further details in supplementary material.
b
Defined according to the Registrar general's classification and included the following categories: professional/managerial, skilled non‐manual, skilled manual, semiskilled/unskilled manual (includes no male head at birth/carer/armed forces/sick/unemployed).