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. 2023 Jan 26;43(5):647–660. doi: 10.1002/pd.6301

FIGURE 4.

FIGURE 4

The Homocysteine‐methionine cycle and trans‐sulfuration pathway. Adapted from Hobbs et al. 2005, Tsitsiou et al. 2011. 30 , 31 , 47 Red – metabolite increased in CHD cases versus controls; Green – metabolite decreased in CHD cases versus controls. SAM – S‐adenosylmethionine; SAH – S‐adenosylhomocysteine; GluCys – glutamylcysteine; GSH – reduced glutathione; GSSG – oxidized glutathione; CysGly – cysteinylglycine.