TABLE 1.

ADA enzyme activities^a in the transduced cells

Vector	Measured ADA enzyme activity, avg proviral copy no./cell, calculated ADA enzyme activity/integrated provirus for:
	B-LCL cells			TJF-2 cells
	Expt 1	Expt 2	Avg ADA/provirusc	Expt 1	Expt 2	Expt 3	Avg ADA/provirus
Noneb	1	2		5	2	1
PA317/LASN	8, 0.5, 16	16, 1.0, 16	16	14, 0.4, 32	30, 1.0, 30	28, 1.0, 28	30
PG13/LASN	51, 3.0, 17	24, 1.2, 20	19	155, 2.0, 76	99, 2.0, 50	43, 2.0, 43	49
PG13/ADA(MPSV)	81, 0.8, 101	79, 0.8, 98	100d	189, 2.4, 79	118, 2.3, 52	136, 2.3, 60	64e
PG13/ADA(SL3-3)	38, 0.9, 43	32, 0.9, 36	40	137, 1.4, 98	53, 1.3, 41	66, 1.1, 60	67e

^aADA enzyme activity is expressed as nanomoles of inosine produced per minute per 10⁸ cells. 

^bValues in this row are measured ADA enzyme activities. 

^cAvg ADA/provirus, average value for calculated ADA enzyme activity per integrated provirus. 

^dP < 0.05 compared with values for PA317/LASN, PG13/LASN, and PG13/ADA(SL3-3). 

^eP < 0.05 compared with values for PA317/LASN and PG13/LASN.