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ADA enzyme activities in the transduced patient’s PBMC
| Vector | ADA enzyme activitya
|
||
|---|---|---|---|
| Expt 1 | Expt 2 | Avg | |
| None | 2 | 0 | 1 |
| PA317/LASN | 36 | 27 | 32 |
| PG13/LASN | 237 | 186 | 212 |
| PG13/ADA(MPSV) | 461 | 568 | 515 |
| PG13/ADA(SL3-3) | 80 | 79 | 80 |
ADA enzyme activity is expressed as nanomoles of inosine produced per minute per 108 cells.
