TABLE 3.
ADA enzyme activities in the transduced TJF-2 cells
| Vector | ADA enzyme activitya
|
|||
|---|---|---|---|---|
| Expt 1 | Expt 2 | Expt 3c | Avg | |
| Noneb | 4 | 4 | 3 | 4 |
| PG13/ADA(MPSV) | 138 | 100 | 98 (1.0) | 112 |
| FLYA13/ADA(MPSV) | 68 | 206 | 232 (2.0) | 167 |
| FLYRD18/ADA(MPSV) | 323 | 308 | 422 (4.8) | 351d |
a
ADA enzyme activity is expressed as nanomoles of inosine produced per minute per 108 cells.
b
Values in this row are measured ADA enzyme activities and proviral copy numbers.
c
Values in parentheses are average proviral copy numbers/cell.
d
P < 0.05 compared with the value for PG13/ADA(MPSV).