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. 2023 Apr 10;33(8):1399–1411. doi: 10.1111/sms.14365

TABLE 5.

Sedentary time and physical activity in relation to cardiac structure and function at age 17 years based on BMI category.

Predictor Left ventricular mass index2.7 Relative wall thickness Left ventricular diastolic function (E/A) Left ventricular filling pressure (E/e′)
β (95% CI) p‐Value β (95% CI) p‐Value β (95% CI) p‐Value β (95% CI) p‐Value
Normal weight < 25 kg/m2
Sedentary time 0.150 (0.051 to 0.250) 0.003 0.051 (−0.075 to 0.176) 0.488 −0.063 (−0.164 to 0.047) 0.247 −0.018 (−0.136 to 0.092) 0.744
Light PA 0.066 (−0.027 to 0.160) 0.161 0.050 (−0.067 to 0.168) 0.436 0.087 (−0.011 to 0.186) 0.083 0.011 (−0.096 to 0.119) 0.910
Moderate‐to‐vigorous PA 0.110 (0.017 to 0.203) 0.021 −0.024 (−0.142 to 0.093) 0.656 −0.026 (−0.125 to 0.073) 0.444 −0.052 (−0.159 to 0.055) 0.341
Overweight/obese ≥ 25 kg/m2
Sedentary time 0.133 (0.041 to 0.230) <0.001 −0.197 (−0.392 to −0.003) 0.047 0.038 (−0.147 to 0.217) 0.710 0.109 (−0.069 to 0.288) 0.258
Light PA 0.017 (−0.057 to 0.180) 0.555 −0.170 (−0.371 to 0.025) 0.086 0.119 (−0.063 to 0.302) 0.193 0.121 (−0.059 to 0.301) 0.186
Moderate‐to‐vigorous PA 0.123 (0.022 to 0.185) <0.001 0.028 (−0.142 to 0.198) 0.746 −0.113 (−0.235 to 0.078) 0.279 −0.122 (−0.280 to 0.036) 0.128

Note: Analyses were conducted using linear regression model and adjusted for age, sex, high‐density lipoprotein cholesterol, low‐density lipoprotein cholesterol, triglyceride, glucose, insulin, heart rate, systolic blood pressure, high‐sensitivity C‐reactive protein, smoking status, family history of cardiovascular and metabolic disease, and sedentary time, light physical activity or moderate‐to‐vigorous physical activity depending on the predictor. β is standardized regression coefficient and PA is physical activity. Statistically significant associations (in bold) were determined by a two‐sided p‐value <0.05.