TABLE 2.
Colonic pH profiles across the dietary intervention periods, including overall and regional colonic pH, as well as pH nadir and peak metrics.
| Control | Sugarcane | Combination | |
|---|---|---|---|
| pH | |||
| Overall | 6.9 (6.6–7.2) | 6.7 (6.2–7.1) | 6.7 (6.4–7.0) |
| Quartile 1 | 6.5 (6.2–6.8) | 6.5 (6.2–6.8) | 6.3 (6.0–6.6) |
| Quartile 2 | 6.9 (6.6–7.2) | 6.7 (6.2–7.2) | 6.9 (6.6–7.1) |
| Quartile 3 | 7.4 (7.0–7.8) | 7.1 (6.7–7.5) | 7.0 (6.7–7.4) |
| Quartile 4 | 7.5 (7.2–7.8) | 7.2 (6.8–7.6) | 7.1 (6.8–7.5) |
| pH nadir and peak metrics | |||
| Nadir | 5.4 (5.4–5.7) | 5.7 (5.4–6.0) | 5.4 (5.2–5.7) |
| Time to nadir (from ileocaecal valve; hours) | 1.5 (0.3–2.7) | 1.3 (0.9–2.1) | 1.7 (0.7–2.1) |
| Time to nadir (% of colonic transit time) | 4.1 (2.3–14.4) | 5.5 (3.8–13.3) | 4.7 (3.6–14.9) |
| Peak | 8.4 (8.2–8.6)a, b | 8.0 (7.7–8.4)a | 7.9 (7.7–8.2)b |
| Time to peak (from ileocaecal valve; hours) | 24.1 (8.8–34.9) | 11.1 (4.0–30.9) | 13.4 (8.8–20.5) |
| Time to peak (% of colonic transit time) | 67.2 (51.9–84.0) | 57.0 (30.8–97.4) | 80.0 (55.6–90.1) |
Note: Data shown as mean (95% CIs) for pH values, median (IQR) for time to pH nadir and peak, and analysed via linear mixed models. Significant differences (p ≤ 0.05) between the dietary interventions shown via shared superscripts.