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. 2023 Nov 1;62(5):707–720. doi: 10.1002/uog.26244

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© 2023 The Authors. Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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UOG-26244-FIG-0006-c — Scatterplots displaying unmyelinated white matter (UWM) shape parameter, before (Timepoint 1 (T1)), 1 week after (Timepoint 2 (T2)) and 6 weeks after (Timepoint 3 (T3)) fetal surgery, in fetuses with open spina bifida (OSB) and specific lesion type/additional central nervous system (CNS) anomaly (, T1; , T2; , T3), OSB fetuses without additional CNS anomaly (, T1; , T2; , T3) and gestational age (GA)‐matched controls (, T1; , T2; , T3). Specific lesion type/additional CNS anomalies were: (b) persistent hindbrain herniation, (c) myeloschisis, (d) heterotopia, (e) heterotopia and corpus callosum anomaly and (f) persistent hindbrain herniation and corpus callosum anomaly. Average GA at surgery indicated by black vertical line.

Inline graphic — Scatterplots displaying unmyelinated white matter (UWM) shape parameter, before (Timepoint 1 (T1)), 1 week after (Timepoint 2 (T2)) and 6 weeks after (Timepoint 3 (T3)) fetal surgery, in fetuses with open spina bifida (OSB) and specific lesion type/additional central nervous system (CNS) anomaly (, T1; , T2; , T3), OSB fetuses without additional CNS anomaly (, T1; , T2; , T3) and gestational age (GA)‐matched controls (, T1; , T2; , T3). Specific lesion type/additional CNS anomalies were: (b) persistent hindbrain herniation, (c) myeloschisis, (d) heterotopia, (e) heterotopia and corpus callosum anomaly and (f) persistent hindbrain herniation and corpus callosum anomaly. Average GA at surgery indicated by black vertical line.