Table 1.
The MIC values of the complexes as evaluated against an extended panel of fungi.
|
|
MIC [μg mL−1] |
|||||
|---|---|---|---|---|---|---|
|
Compounds |
C. albicans |
C. neoformans |
Candida tropicalis |
C. glabrata |
C. deuterogattii |
C. auris |
|
ATCC 90028 |
ATCC 208821 |
ATCC 750 |
ATCC 90030 |
ATCC 32609 |
CBS10913 |
|
|
Pd1 |
0.25–0.5 |
0.125 |
0.125 |
0.06–0.125 |
0.25 |
0.03–0.125 |
|
Pd2 |
≤0.25 |
≤0.25 |
1.0 |
16 |
0.016 |
0.25 |
|
Pd3 |
16 |
0.5 |
n.d. |
n.d. |
n.d. |
n.d. |
|
Pd4 |
0.5–2 |
0.125–0.25 |
0.5–1 |
1–2 |
0.25–1 |
0.06–1 |
|
Pd5 |
4–8 |
0.5–1 |
8–16 |
8–16 |
4–2 |
4–2 |
|
Pd6 |
>32 |
>32 |
n.d. |
n.d. |
n.d. |
n.d. |
|
Pd7 |
0.25–1 |
<0.25 |
1 |
0.5–1 |
0.5–1 |
0.5–1 |
|
Pd8 |
0.5–1 |
0.06–0.25 |
0.5 |
1–2 |
0.25–0.5 |
0.25–1 |
|
Pd9 |
0.5–1 |
0.125 |
0.5–1 |
0.5–2 |
0.25–0.5 |
0.5–2 |
|
Pd10 |
0.25–1 |
0.25 |
0.5–1 |
0.5–2 |
0.5–2 |
0.5–2 |
|
Pd11 |
2–4 |
1 |
2–4 |
8 |
2 |
1–4 |
|
fluconazole |
0.25–0.5 |
8 |
4 |
>32 |
>32 |
≥32 |